

PDGF appeals to people who want to do more for their skin. It supports skin renewal, improves texture, and encourages collagen production for results that look polished, healthy, and natural over time.
At Sarasota Premier Aesthetics, we use platelet-derived growth factor, both by itself and after microneedling, to support skin rejuvenation, tissue repair, and the skin’s natural healing process. This treatment is perfect for patients who want smoother texture, better glow, and stronger support for collagen production. It’s a regenerative option for patients in Sarasota, FL, and Lakewood Ranch, FL who want thoughtful care, minimal downtime, and results that build naturally.
Platelet-derived growth factor (PDGF) is one of several growth factors that help with wound healing, cell growth, and tissue regeneration in the body. It plays a vital role in how the body responds to injury by supporting cell proliferation, tissue repair, and the formation of new blood vessels.
After microneedling creates tiny controlled channels in the skin, pure PDGF can be applied topically to help enhance healing, support skin regeneration, and encourage smoother, healthier-looking skin.

Microneedling is already one of the most effective aesthetic treatments for improving skin texture, softening wrinkles, and stimulating collagen production. It works by creating controlled micro-injuries in the skin, which encourages the body to begin healing, increase collagen and elastin production, and support a firmer, fresher look over time.
Adding PDGF treatments after microneedling gives the skin extra support during recovery. PDGF helps guide the skin through the healing process by supporting other cells involved in repair, including endothelial cells and smooth muscle cells. In simple terms, PDGF helps the body do what it already does well. It supports faster healing, helps reduce inflammation, and may help patients see improved texture and better overall skin health as their results develop.
This pairing makes sense for patients who want to enhance results from microneedling without needing a blood draw.

At Sarasota Premier Aesthetics, we believe good skin care should make sense for your real life. You do not need to chase every new treatment. You need the right one for your skin, your goals, and your schedule.
Our team takes time to understand your concerns and build a personalized treatment plan. We focus on patient safety, natural-looking improvement, and treatments that support healthy skin over time. Patients in Sarasota and Lakewood Ranch come to us for advanced non-surgical care that feels personal, comfortable, and realistic.
PDGF is a great fit for patients who want to support skin healing after microneedling, improve skin elasticity, and work toward overall rejuvenation with a proven approach that fits easily into a modern skin plan.
PDGF has a key role in how the body repairs tissue. In the skin, PDGF binds to specific receptors on target cells. That interaction helps trigger signals linked to cell proliferation, tissue regeneration, and the formation of blood vessels that support healthy repair. These processes are part of normal wound healing and help explain why PDGF has become a popular option after microneedling.
This matters because microneedling starts a repair response. PDGF helps support that response. It can help accelerate healing, encourage collagen and elastin, and support the skin as it works toward better tone, smoother texture, and stronger skin elasticity.
When used after microneedling, PDGF may help improve:
Many patients also choose PDGF because they want help maintaining healthy skin and a more refreshed look without trying to change everything about their face. It is a subtle step that can support a more polished result.

Patients are often drawn to PDGF because it adds extra support to the skin after treatment without making the process more complicated.
Benefits may include:
For many patients, this is an easy way to give the skin more support after microneedling while still keeping the treatment simple.
A common question is how PDGF compares to platelet-rich plasma or PRF.
Platelet-rich plasma uses the patient’s own blood. That means a blood draw is needed before treatment, and the provider processes the sample to separate the healing components from the rest of the blood. PRF works in a similar way, also relying on the patient's blood and platelet concentration.
PDGF does not require a blood draw. That is one reason some patients prefer it. They want regenerative support without using their own blood, and they like that the treatment can be applied in a simple, streamlined way after microneedling.
For some patients, PRP or PRF still makes sense. Others prefer Ariessence pure PDGF because it is easy to add to treatment and supports the same general goal: helping the skin heal well and look better over time.

PDGF after microneedling is most often used on the:
In some cases, it may also be used on other areas where skin rejuvenation, tissue regeneration, or scar support is the goal. It can even be part of broader regenerative conversations around concerns like hair loss, depending on the overall treatment approach, though this page is focused on post-microneedling skin support.

PDGF can also be a great addition after laser rejuvenation treatments. Just like it is used after microneedling, it helps support the skin’s natural healing process after treatment. That added support can help enhance healing, improve downtime, and encourage better overall results as the skin recovers.
For patients who want to get more out of their laser treatment, PDGF offers a regenerative way to support skin renewal while keeping the treatment plan thoughtful and efficient. It can be a strong option when the goal is smoother recovery, healthier-looking skin, and results that come together in a more supported way.
PDGF may be a good fit for most patients who are already good candidates for microneedling and want extra support for:
It can be a strong option across many skin types, especially for patients who want minimal downtime and a treatment that supports the skin's unique healing response.
During your consultation, we will look at your skin, talk through your goals, and decide if PDGF should be part of your plan.

On the day of treatment, your skin is cleansed, and numbing cream is usually applied. Microneedling is then performed to create tiny channels in the skin. Afterward, PDGF is applied topically to support the skin during recovery.
The treatment itself is straightforward. There is no blood draw, no need to process the patient's blood, and no added complexity for patients who want regenerative support after microneedling.
After treatment, your skin may look pink or slightly red. It may also feel warm, tight, or a little sensitive for a short time. This is normal.
The good news is that recovery is usually easy to manage. Most patients have minimal downtime and can return to normal activities quickly, with a few simple precautions. We may ask you to:
This phase matters. Good aftercare helps enhance healing and supports better results.

This is where honest expectation-setting matters. PDGF is not meant to create a dramatic overnight shift. It supports your skin as it heals and renews.
Some patients notice that their skin looks fresher once the first phase of healing settles. More noticeable changes in tone, texture, and firmness tend to build over time as collagen production and elastin production continue. In other words, results develop gradually.
That is usually how the best skin treatments work. One session can be a great start. A series often creates the significant improvements patients are hoping for. If your goal is smoother texture, softer lines, and more resilient skin, consistency matters.
Patients today want treatments that work with the body. They want smoother texture, healthier skin, and a more refreshed look that still feels like them.
That is why regenerative options keep getting attention. Treatments like PDGF support processes the body produces on its own, including healing, cell growth, and collagen renewal. They fit well into a modern approach to maintaining youthful skin because they support the skin instead of asking it to do too much at once.
For patients in Sarasota and Lakewood Ranch, PDGF after microneedling is a smart option when the goal is better skin health, a youthful appearance, and support for healthy skin that lasts.
Platelet-derived growth factor is a protein involved in wound healing, cell growth, and tissue repair. In aesthetics, it is often used after microneedling to support skin recovery.
PDGF supports the skin’s natural healing process, encourages collagen and elastin production, and may help improve skin texture as the skin recovers.
No. Unlike platelet-rich plasma, PDGF does not require a blood draw or processing of the patient's blood.
No. PRP uses the patient's blood. PDGF is a separate regenerative option used to support healing and recovery after treatment.
Some patients notice an early glow after healing, while bigger changes usually take more time. Results develop gradually as the skin continues to repair and build collagen.
Yes, it may help improve the look of acne scars when used as part of a microneedling-based treatment plan.
Many skin types can benefit from PDGF after microneedling, but the best way to know is through a consultation.
Ariessence Pure PDGF is one branded PDGF option used in aesthetic settings to support healing and regeneration after procedures like microneedling.